What is ANUA PDRN Hyaluronic Acid 100 Moisture Cream?
ANUA PDRN Hyaluronic Acid 100 Moisture Cream is a soft, silky face cream from ANUA that combines PDRN with a blend of many forms of hyaluronic acid. It is designed to flood thirsty skin with moisture, then hold it there, leaving the face plump, smooth and comfortable without a greasy film. Squalane, niacinamide, hydrolysed collagen, adenosine and centella derivatives round out the formula. It comes in a 60ml jar for everyday use and a 10ml mini that is ideal for trying it first or travelling.
It belongs to ANUA's PDRN line, which was created around the idea of supporting skin recovery and bounce as well as hydration. The cream is the sealing step of that routine, used after toner and serum.
What is PDRN in skincare?
PDRN stands for polydeoxyribonucleotide, a DNA-derived ingredient listed on this pack as sodium DNA. In skincare it is valued for supporting the look of healthy, resilient skin. Cosmetic PDRN is usually derived from salmon; if you avoid fish-based ingredients, look closely at the pack. Learn more in our PDRN skincare guide.
What does "Hyaluronic Acid 100" mean?
The name points to the cream's heavy focus on hyaluronic acid. The ingredient list includes many different types, from sodium hyaluronate and hydrolysed hyaluronic acid to crosspolymer and acetylated forms. Different sizes and forms hold water at different levels of the skin's surface, which is why multi-type blends feel more evenly hydrating.
ANUA PDRN Cream benefits: what it does for your skin
This is a comfort cream first: it is all about deep, lasting hydration with a healthy glow.
Deep, multi-layer hydration
The many forms of hyaluronic acid, plus glycerin and diglycerin, draw water into the skin's surface, while squalane helps keep it from escaping. Skin feels cushioned and supple for hours.
Smoother, plumper-looking skin
Well-hydrated skin looks smoother, and fine dryness lines become less visible. Adenosine and hydrolysed collagen support a firmer, bouncier feel over time.
Supports skin recovery
PDRN, centella derivatives such as madecassoside and asiaticoside, and aloe are included to support skin that feels stressed from sun, air-conditioning or active treatments.
A dewy, healthy glow
The finish is radiant rather than matte, giving that fresh "glass skin" look many people want, without heaviness.
Helps skin look more even
Niacinamide, high in the ingredient list, supports a more even-looking tone and a stronger skin barrier with regular use.
ANUA PDRN Cream key ingredients
| Ingredient | What it does |
|---|---|
| Sodium DNA (PDRN) | Supports the look of resilient, recovering skin |
| Multiple forms of hyaluronic acid | Attract and hold water for layered hydration |
| Squalane | A lightweight lipid that softens skin and reduces moisture loss |
| Niacinamide | Supports an even tone and stronger barrier |
| Hydrolysed collagen and adenosine | Support a smoother, firmer feel |
| Madecassoside, asiaticoside, centella | Soothe and calm |
Is it fragrance-free?
No added fragrance appears in the ingredient list, which makes it a good candidate for sensitive skin. The formula does include several plant extracts, so patch-testing is still sensible for very reactive skin. Discover more hydrating options in our hyaluronic acid edit.
Is ANUA PDRN Cream good for your skin type?
It is built for dry and dehydrated skin, but the amount you use makes it work for others too.
Is it good for dry skin?
Yes, this is where it performs best. Dry, flaky or tight skin feels comforted straight away, and regular use leaves the face softer and smoother. In winter, a slightly thicker layer at night works well.
Is it good for oily skin?
It can be, with a light hand. Oily skin is often dehydrated underneath, and a thin layer gives moisture without heaviness. In humid summers, many oily skin types prefer it only at night, with a gel moisturiser during the day.
Is it good for acne-prone skin?
It is not an acne treatment, but its lightweight, oil-light texture and soothing ingredients make it comfortable for acne-prone skin that is dried out by acne products. ANUA does not publish a formal non-comedogenic test, so introduce it slowly and watch how your skin responds.
Is it good for sensitive skin?
Generally yes. No added fragrance and calming centella derivatives help, though anyone with known plant-extract sensitivities should patch-test first.
Is it good for mature skin?
Yes. Mature skin often loses moisture more easily, and the combination of hyaluronic acid, PDRN, collagen and adenosine supports a plumper, smoother look. Pair it with a dedicated treatment for deeper lines; see our ageing skincare edit.
Who should patch-test first or skip it?
Patch-test on the jawline for a day if your skin is very reactive. Check the source of PDRN if you avoid fish-derived ingredients. If you are pregnant, the formula contains no retinoids, but it is always wise to review a new routine with your doctor.
How to use ANUA PDRN Cream (morning and night)
Use it as the final skincare step, morning and night.
Morning routine
- Cleanse, then apply a toner such as the ANUA Heartleaf 77% Soothing Toner.
- Add any serum.
- Take a pea-sized amount, warm it between your fingertips and press it over the face and neck.
- Finish with sunscreen.
Evening routine
- Remove sunscreen with the ANUA Heartleaf Pore Control Cleansing Oil, then cleanse.
- Layer toner and serum; if you use retinol, give it a minute to settle.
- Seal everything in with a slightly more generous layer of cream.
How much and how often?
A pea-sized amount covers the face in summer; use a little more in winter. It is gentle enough for twice-daily use.
What to pair it with
It works beautifully over hydrating layers like the ANUA Rice 70 Glow Milky Toner and brightening serums such as the ANUA Peach 70% Niacinamide Serum. Because it contains no exfoliating acids, it also pairs safely with retinoids and acid treatments.
Hyaluronic acid in a moisturiser: your questions answered
Is "100" hyaluronic acid good for skin?
The number refers to the cream's hyaluronic acid focus, not to a 100% concentration. A blend of many forms in a balanced formula is good for most skin, because it hydrates without the sticky feel of a very concentrated product.
Can hyaluronic acid dry out skin?
It can feel that way if it is used alone in very dry air, because it pulls water but has nothing to seal it in. This cream solves that by pairing hyaluronic acid with squalane and other moisture-locking ingredients.
Is hyaluronic acid in a moisturiser enough?
For many people, yes. Dry or dehydrated skin may like an extra hydrating serum underneath, but a hyaluronic acid cream alone already covers daily hydration needs for normal and combination skin.
How much hyaluronic acid cream should you use?
More is not better. A pea-sized amount is enough for the whole face on most days, and a little extra on dry cheeks in winter. Using too much simply leaves a film on the surface that can feel tacky in humid weather and may pill under sunscreen or makeup. If your skin still feels tight after a pea-sized layer, add a hydrating toner or serum underneath rather than doubling the cream.
Should you use a moisturiser after a hyaluronic acid serum?
Yes. A serum attracts water; a cream like this one seals it in. Apply the cream within a minute or two of the serum, while skin is still slightly damp.
ANUA PDRN Cream results: how long until you see a difference?
Skin feels softer and more comfortable immediately after the first use. Within one to two weeks, most people notice smoother texture and fewer tight, dry patches. A plumper, more radiant look builds over four to six weeks of consistent use.
Does ANUA PDRN Cream have side effects?
Side effects are uncommon. Very oily skin may find it too rich in humid weather; simply use less or switch to night-only use. Rarely, plant extracts can cause irritation, so stop if redness, itching or bumps appear.
ANUA PDRN Cream price in Pakistan
Live prices for the 10ml mini and the 60ml jar are shown at the top of this page. The mini is a smart way to test it, and the full jar is better value once it becomes part of your routine.
Original vs fake ANUA PDRN Cream: how to check
As one of ANUA's newer bestsellers, this cream is worth checking carefully. Authentic jars have crisp printing, matching batch and expiry codes on the box and container, and a lid that seals snugly. The cream itself should be smooth, evenly coloured and almost scent-free; a gritty feel, separation or a perfumed smell are warning signs.
Shopping with a reliable source removes the doubt. YESBEAUTY is an authentic seller of ANUA in Pakistan, with this cream sourced directly from ANUA's official distribution channels in Seoul, Korea. We are part of the Korean Skincare group, serving more than 200,000 customers over 10 years, and offer a 7-day return guarantee if a product is ever found inauthentic. Read The YESBEAUTY Authenticity Promise.
ANUA PDRN Cream vs other moisturisers
| Cream | Texture | Best for | Key ingredients |
|---|---|---|---|
| ANUA PDRN Hyaluronic Acid 100 Cream | Silky cream | Dry, dehydrated, stressed skin | PDRN, hyaluronic acid, squalane |
| Medicube Collagen Jelly Cream | Bouncy jelly | Glow, plumpness | Collagen |
| Dr.Althea 345 Relief Cream | Light cream | Sensitive, redness-prone skin | Soothing complex |
| CeraVe Moisturising Cream | Rich cream | Very dry skin, barrier care | Ceramides |
ANUA PDRN Cream vs Medicube
The Medicube Collagen Jelly Cream has a bouncier, jelly-like texture focused on glow, while the ANUA cream feels creamier and leans more on deep hydration and recovery. Choose Medicube for a lighter, dewy feel and ANUA for drier skin.
Cream vs serum: which do you need?
The matching PDRN serum delivers concentrated hydration in a thin layer, while this cream seals moisture in and adds comfort. Dry skin benefits from both; combination skin can often use just one.
Other options for sensitive or very dry skin
For reactive skin, the Dr.Althea 345 Relief Cream is a calming pick. For very dry, barrier-damaged skin, the CeraVe Moisturising Cream or the Purito Seoul Mighty Bamboo Panthenol Cream offer richer support.
Best moisturiser for dry skin in Pakistan: where this one fits
Pakistan's winters, dusty air and air-conditioned offices all pull moisture from the skin. A cream that combines strong hydrators with moisture-locking ingredients is the most reliable fix, and this one is among the most comfortable options. Compare more choices in our moisturisers collection and the full ANUA range.
How should you store it in Pakistan's heat?
Keep the jar tightly closed, away from direct sun and out of hot places such as a car dashboard. Use a clean, dry finger or spatula to scoop it, and use it within the period shown on the open-jar symbol.
