What is Centellian24 Expert Madeca Cream Active Renew PDRN?
This is the PDRN edition of Centellian24's famous Madeca Cream, a Korean pharmacy-brand moisturiser built on centella. This version combines two headline ingredients: PDRN (listed as sodium DNA) and TECA, the brand's purified blend of centella compounds. Around them sit niacinamide, a complex of several hyaluronic acids, panthenol, ceramide NP and adenosine.
The result is a rich yet smooth 50ml cream aimed at skin that feels dry, stressed or less resilient, and at those first fine lines that show more when skin is dehydrated.
What is Madeca Cream?
Madeca Cream is Centellian24's signature line, named after madecassic acid, one of the active compounds in centella asiatica. The original Time Reverse cream made the line famous; Active Renew PDRN builds on it with PDRN and extra hydrating and barrier ingredients.
Is it a moisturiser?
Yes. Despite the treatment-style ingredients, it is used exactly like a moisturiser: as the final skincare step, morning and/or evening.
Centellian24 Expert Madeca Cream Active Renew PDRN benefits: what it does for your skin
Comfort for stressed skin
TECA's centella compounds, madecassic acid and asiaticoside, help skin that feels irritated after retinoids, acids, sun or harsh weather calm down.
A healthier, more resilient look
PDRN is used in Korean skincare for tired, less bouncy skin, supporting a smoother and fresher-looking complexion over time.
Deep, layered hydration
Multiple types of hyaluronic acid, glycerin and panthenol hydrate at different depths, so skin feels plump rather than tight.
Barrier support
Ceramide NP, phytosphingosine and niacinamide help hold moisture in and keep the skin feeling stronger.
Smoother-looking fine lines
Adenosine, combined with better hydration, helps early fine lines look softer.
Centellian24 Expert Madeca Cream Active Renew PDRN key ingredients
| Ingredient | What it does |
|---|---|
| PDRN (sodium DNA) | Helps skin look smoother, fresher and more resilient |
| TECA (centella compounds incl. madecassic acid and asiaticoside) | Calms and comforts stressed-feeling skin |
| Niacinamide | Barrier support and a more even-looking tone |
| Hyaluronic acid complex | Long-lasting hydration at several depths |
| Panthenol, ceramide NP | Softness and moisture retention |
| Adenosine | Helps fine lines look smoother |
The formula also contains lavender, citrus, rosemary and chamomile oils, which give it a light natural scent. Sensitive skin should note this.
How to use Centellian24 Expert Madeca Cream Active Renew PDRN (morning and night)
Morning
- Wash your face and apply toner and serum.
- While the skin is still slightly damp, warm a pea-sized amount between your fingertips.
- Massage it gently over the face and neck.
- Wait a minute, then apply a broad-spectrum sunscreen.
Evening
- Double cleanse to remove sunscreen and makeup.
- Follow with toner, then your serum or treatment (retinol, for example).
- Once those have absorbed, massage in the cream, using a little extra on dry cheeks.
- For the delicate eye area, use a dedicated product like the Centellian24 360 Shot PDRN Lifting Eye Cream.
When to use Madeca cream?
Morning, evening or both. In humid Pakistani summers a thin layer at night is often enough for combination skin; in winter or in air-conditioned rooms, dry skin benefits from using it twice a day.
Centellian24 Expert Madeca Cream Active Renew PDRN results: how long until you see a difference?
Skin feels softer, plumper and more comfortable from the first application. After one to two weeks of steady use, stressed or tight skin usually feels calmer and better able to tolerate actives. A smoother texture and softer-looking fine lines take longer, typically four to eight weeks. Results vary from person to person.
Does Centellian24 Expert Madeca Cream Active Renew PDRN have side effects?
It suits most dry and stressed skin, but two points matter. First, the essential oils (lavender, citrus, rosemary) can bother very sensitive or allergy-prone skin, so try it on a small patch of the jaw for a day before using it all over. Second, it is a rich cream, so very oily or breakout-prone skin may feel congested in summer. If that happens, use a thin layer at night only.
Is it good for sensitive skin?
Centella and panthenol are calming, but because of the essential oils, people with fragrance sensitivity may prefer a fragrance-free barrier cream such as the Purito Seoul Mighty Bamboo Panthenol Cream.
Which skin types does it suit?
Dry and dehydrated skin
The best match: a rich but comfortable cream that keeps skin hydrated for hours.
Maturing skin
PDRN, adenosine and layered hyaluronic acid target the dull, less bouncy look and early lines.
Skin stressed by actives
If retinol or acids leave you tight and flaky, this cream helps cushion the skin.
Oily and combination skin
Use sparingly, at night, or only on drier areas in summer.
Centellian24 Expert Madeca Cream Active Renew PDRN vs Time Reverse
Both creams share Centellian24's TECA centella base, but they are built for slightly different needs.
| Feature | Expert Madeca Active Renew PDRN | Madeca Cream Time Reverse |
|---|---|---|
| What is inside | PDRN, centella TECA, niacinamide, ceramide and several hyaluronic acids | Centella TECA and adenosine |
| Who it suits | Stressed, thirsty or ageing-looking skin | Normal to dry, ageing-looking skin |
| Size options | One 50ml jar | A 15ml mini or a 50ml jar |
Choose Active Renew PDRN for the added PDRN and extra hydration and barrier care. Choose Time Reverse for the classic formula, or to try the line in a small size first.
Other creams to compare
For a fragrance-free soothing cream, consider the Dr.Althea 345 Relief Cream; for very dry body-and-face use, the CeraVe Moisturizing Cream; and for a bouncy gel-cream, the Medicube Collagen Jelly Cream.
Centellian24 Madeca Cream Active Renew PDRN price in Pakistan
The current price for the 50ml jar is shown on this page. With a pea-sized amount once or twice a day, one jar typically lasts six to ten weeks.
Original vs fake Centellian24 Expert Madeca Cream Active Renew PDRN: how to check
As one of Korea's best-known pharmacy creams, Madeca products are a target for counterfeiters. First look at the box: print should be sharp, the seal intact and the batch and expiry codes legible and matching the container. Then check the cream itself, which should be smooth, rich and spread evenly with a light herbal scent. If it is watery, separated, grainy or smells sour, do not use it.
YESBEAUTY is an authentic seller of Centellian24 in Pakistan; all our stock is sourced directly from Centellian24's official distribution channels in Seoul, Korea. If a product is ever shown to be inauthentic, our 7-day return guarantee protects your purchase. Read The YESBEAUTY Authenticity Promise or see all Centellian24 products.
Best PDRN moisturiser in Pakistan: where it fits
If your skin feels dry, tired and less resilient, and you want centella and PDRN in one step, this cream is a strong choice. Explore more in our PDRN, Ageing, Dryness and Moisturisers collections.
Storage
Close the lid tightly, use a clean spatula or dry fingers, and keep the jar away from heat and direct sunlight. Dipping wet fingers into a jar introduces water and bacteria, which shortens the life of the cream, so a small spatula is worth keeping beside it on your dressing table.
